منابع مشابه
Pathophysiology of portal hypertension.
Portal hypertension is a common clinical syndrome associated with chronic liver diseases, and is characterized by a pathological increase in portal pressure that leads to the formation of portosystemic collaterals resulting in shunting of portal blood into the systemic circulation. The increase in portal pressure is due to an increase in vascular resistance and an elevated portal blood flow. Th...
متن کاملPathophysiology of Portal Hypertension and Esophageal Varices
Esophageal varices are the major complication of portal hypertension. It is detected in about 50% of cirrhosis patients, and approximately 5-15% of cirrhosis patients show newly formed varices or worsening of varices each year. The major therapeutic strategy of esophageal varices consists of primary prevention, treatment for bleeding varices, and secondary prevention, which are provided by phar...
متن کاملCurrent concepts on the pathophysiology of portal hypertension.
Cirrhosis of the liver is by far the most common cause of portal hypertension in the western world. Portal hypertension is a frequent clinical syndrome, defined by a pathological increase in the portal venous pressure. When the portal pressure gradient (the difference between pressures in the portal and the inferior vena cava veins: normal value below 6 mmHg) increases above 10-12 mmHg, complic...
متن کامل[Portal hypertension in pediatrics. I: pathophysiology and clinical aspects].
Portal hypertension causes serious and life-threatening complications. It is produced by increased resistance to blood flow through the portal axis, with a gradient to inferior vena cava higher than 5 mmHg. When this is 10 to 12 mmHg there is risk of bleeding from esophageal varices. In pediatric patients two different models exist: prehepatic (without liver disease), and intrahepatic (with liv...
متن کاملPortal circulation and portal hypertension.
During the last 25 years, there have been important developments in visualising the portal vein, in examining its contents, and in measuring the pressure of blood flowing within it. Radiologists have set the scene and now is the time of the scanner. These technical advances have been applied to the diagnosis and treatment of patients with portal hypertension, and many ingenious surgical techniq...
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ژورنال
عنوان ژورنال: Clinics in Liver Disease
سال: 2014
ISSN: 1089-3261
DOI: 10.1016/j.cld.2013.12.001